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Single cell multimodal analysis and machine learning define haematopoietic progenitor and
HSC-like
cells derived in vitro from human pluripotent stem cells. Fidanza et al., 2020, Blood |
A novel human pluripotent stem cell-based gene activation system identifies IGFBP2 as a
mediator in the
production of hematopoietic progenitors in vitro Petazzi et al., 2024, eLife |
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scRNA-seq
Day 13 suspension cells |
CRISPRa
CRISPR-activated cells |
CITE-seq
Day 10+13 suspension cells |
IGFBP2
IGFBP2-treated cells |
CITE-seq + label transfer
Day 10+13 |
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